Disulphide interchange reactions.
نویسندگان
چکیده
منابع مشابه
Assisted refolding of recombinant prochymosin with the aid of protein disulphide isomerase.
Protein disulphide isomerase (PDI) was shown to be able to accelerate the refolding of unfolded recombinant prochymosin and to enhance the overall yield of active protein. Unlike previous reports in this study PDI was found to be active at pH values as high as 11. The coincidence of the similar apparent optimum pH values of uncatalysed and PDI-catalysed reactions suggests that conditions favour...
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Key factors that mediate vascular smooth muscle cell proliferation and migration are platelet-derived growth factor (PDGF) and thrombospondin 1 (TSP1). We now report that PDGFBB bound tightly and specifically to TSP1, that this interaction was markedly dependent on the disulphide bond arrangement in TSP1, and that binding of PDGFBB to TSP1 did not preclude PDGFBB from binding to its receptor on...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 60 4 شماره
صفحات -
تاریخ انتشار 1954